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Issue:ISSN 1000-7083
          CN 51-1193/Q
Director:Sichuan Association for Science and Technology
Sponsored by:Sichuan Society of Zoologists; Chengdu Giant Panda Breeding Research Foundation; Sichuan Association of Wildlife Conservation; Sichuan University
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Your Position :Home->Past Journals Catalog->2003 Vol.22 No.1

Application of Acute Normovoletic Hemodilution During Orthotopic Liver Transplantation in Pigs
Author of the article:QU Qiang1, WANG Xiao-bin1, TANG Xian-ling1, DING Yu-hui1, HE Chuan-shui2, HE Yan-zheng2
Author's Workplace:(1.Department of Anesthesiology, The Affiliated Hospital of Luzhou Medical College, Luzhou, Sichuan Province 646000, China; 2. Hematology Surgery, Affiliated Hospital of Luzhou Medical College, Luzhou, Sichuan Province 646000, China)
Key Words:liver transplantation; hemodynamics; acute normovoletic hemodilution (ANH); pig; HAES-steril
Abstract:Objective To observe the changes of hemodynamic and coagulation function during orthotopic liver transplantation after application of acute normovoletic hemodillution (ANH) with HAES-steril 6%. Methods Sixteen healthy pigs with weight of 2030 kg wre randomly allocated into Group Ⅰ(control group, n=9) and Group Ⅱ(experiment group, n=7). The vono-venous bypass was established during anhepatic stage. In the operation period, normal maintenance fluids and collection of blood would be administered in both 2 groups, but HAES-steril 6^ applied to ANH before anhepatic stage in Group Ⅱ. The right carotic artery was cannulated for blood pressure monitoring and collection of blood biochemical sample in perioperation period. Result The hemodynamic and coagulation function of all pigs were normal during perioperation period in both 2 groups. Conclusion There is no obviously changes in the blood coagulation and the hemodynamics after application of ANH during orthotopic liver tansplantation.
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