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Issue:ISSN 1000-7083
          CN 51-1193/Q
Director:Sichuan Association for Science and Technology
Sponsored by:Sichuan Society of Zoologists; Chengdu Giant Panda Breeding Research Foundation; Sichuan Association of Wildlife Conservation; Sichuan University
Address:College of Life Sciences, Sichuan University, No.29, Wangjiang Road, Chengdu, Sichuan Province, 610064, China
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Your Position :Home->Past Journals Catalog->2011 Vol.30 No.2

Association between the Tibetan Mastiff Monoamine Oxidase B Gene Single Nucleotide Polymorphism and Stranger-directed Aggressive Behaviour
Author of the article:DING Xiao-lin, MA Da-jun, ZHANG Hui-dong
Author's Workplace:(Nanjing Policedog Institute of the Ministry of Public Security, Nanjing 210012, China)
Key Words: canine; monoamine oxidase B gene; SNP; aggressive behavior
Abstract:The aggressive behavior in Tibetan mastiffs and Labrador retrievers when approached directly by a stranger was tested by a behavioural test. The polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was adopted to detect monoamine oxidaesB (MAOB) gene exon 3 polymorphism, and their genotypes and allelic frequency were estimated among Tibetan mastiffs (aggression when a stranger approaches) and Labrador retrievers (non-aggression when a stranger approaches). These results indicated that genotypes and allelic frequency of the MAOB gene were not significantly different between the two breeds (P>0.05). The result of χ2 showed that the Tibetan mastiff is biased significantly from Hardy-Weinberg equilibrium (P<0.01), while the Labrador retriever fits the Hardy-Weinberg equilibrium (P>0.05). Thus the behavioral differences seen in Tibetan mastiffs and Labrador retrievers when a stranger approaches may not relate directly to the MAOB gene T199C polymorphism.
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