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Issue:ISSN 1000-7083
          CN 51-1193/Q
Director:Sichuan Association for Science and Technology
Sponsored by:Sichuan Society of Zoologists; Chengdu Giant Panda Breeding Research Foundation; Sichuan Association of Wildlife Conservation; Sichuan University
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Your Position :Home->Past Journals Catalog->2010 Vol.29 No.3

Initial Study of Extracts of Bassia rapa L. on Hyperlipemia in Rats
Author of the article:PI Ning-ning1, JIANG Si-ping2, CHEN Zhi-juan1, Zhang Wen-jie1, SU Dong-hai1, XIE Yue1, GAO Ping1*
Author's Workplace:(1.College of Life Sciences, Sichuan University, Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu 610064,China;2. Tibet Plateau Institute of Biology, Lhasa 850001, China)
Key Words:Bassia rapa L.; anti-hyperlipidemia; total cholesterol (TC); triglyceride (TG); high-density lipoprotein cholesterol (HDL-C); low density lipoprotein cholesterol (LDL-C)
Abstract:To investigate the anti-hyperlipidemia effect of Bassia rapa L. on experimental hyperlipemia rats, SD rats were divided into 9 groups, consisting of one normal group (control), one hyperlipemia model group, a positive group, 3 groups receiving 95% ethanol extract (EE95), and 3 groups receiving a water extract of residue (WE) ofBassia rapa L. at 400 mg/kg·d, 800 mg/kg·d, and 1600 mg/kg·d, respectively. Levels of TC, TG, LDL-C and HDL-C in the serum were quantitatively measured. The results showed that EE95 and WE could reduce the content of TC, TG, LDL-C and HDL-C in varying degrees. After treatment with EE95 and WE, TC and TG were reduced remarkably, while the level of HDL-C increased. Compared to the model group, the level of LDL-C was reduced significantly in the EE95 group at 1600 mg/kg·d. But both EE95 and WE had no effect on the liver index of rats.
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