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Issue:ISSN 1000-7083
          CN 51-1193/Q
Director:Sichuan Association for Science and Technology
Sponsored by:Sichuan Society of Zoologists; Chengdu Giant Panda Breeding Research Foundation; Sichuan Association of Wildlife Conservation; Sichuan University
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Your Position :Home->Past Journals Catalog->2017 Vol.36 No.1

Effect of Cold Exposure on the Expressions of PPARα, COXⅡ and PGC-1α in Tupaia belangeri
Author of the article:HOU Dongmin1, ZHANG Di2, YU Tingting1, WANG Zhengkun1, GAO Wenrong1, ZHU Wanlong1*
Author's Workplace:1. Key Laboratory of Ecological Adaptive Evolution and Conservation on Animals-Plants in Southwest Mountain Ecosystem of Yunnan Province Higher Institutes College, School of Life Sciences, Yunnan Normal University, Kunming 650500, China;
2. Yunnan College of Business Management, Kunming 650106, China
Key Words:Tupaia belangeri; adipose tissue; cold exposure
Abstract:In order to investigate whether the adipose tissue of Tupaia belangeri would be transformed under cold acclimation, the mass of adipose tissue, changes of peroxisome proliferator-activated receptor α (PPARα), cyclooxygenase-2 (COXⅡ) and peroxisome proliferators-activated receptor-γ coactivator-1 (PGC-1α) genes were measured in the present study. The results showed that mass of brown adipose tissue and omental white adipose tissue, the mRNA expressions of PPARα, COXⅡ and PGC-1α genes were increased extreme significantly under cold exposure compared with control (P<0.01). And these indicated that the increased expressions of PPARα, COXⅡ and PGC-1α genes under cold condition may cause the transformation of white adipose tissue to browning beige adipocyte, which then transformed to brown adipose tissue and increase the level of uncoupling protein 1 in brown adipose tissue.
2017,36(1): 34-38 收稿日期:2016-08-31
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