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Issue:ISSN 1000-7083
          CN 51-1193/Q
Director:Sichuan Association for Science and Technology
Sponsored by:Sichuan Society of Zoologists; Chengdu Giant Panda Breeding Research Foundation; Sichuan Association of Wildlife Conservation; Sichuan University
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Your Position :Home->Past Journals Catalog->2014 Vol.33 No.4

Investigation of Glycosylated Hemoglobin Levels in Cynomolgus
Author of the article:SUN Ying1,3, ZHANG Xiujuan2, SUN Yunxiao2*, JI Fang2, LIU Xiaoming2
Author's Workplace:(1. South China Botanical Garden, Guangzhou 510650, China; 2. Entomological Institute, Guangzhou 510260, China; 3. University of Chinese Academy of Sciences, Beijing 100049, China)
Key Words:cynomolgus; type 2 diabetes; glycosylated hemoglobin
Abstract:Objective  To investigate the glycosylated hemoglobin (HbA1c) level of cynomolgus monkeys and establish the background database. Methods  Saphenous venous blood of hind legs were collected and then the HbA1cvalues of 176 cynomolgus monkeys (male, 88; female, 88) were determined by high performance liquid chromatography (HPLC). Results  The mean HbA1cvalue of male monkeys was significantly higher than that of female monkeys (4.80%± 0.56% vs. 4.61%±0.55%) (P<0.05). Additionally, the HbA1clevels of cynomolgus monkeys were also significantly different between ages (P<0.05). The mean HbA1cvalue of young female and male monkeys was significantly higher than the elderly group (P<0.05), however, no significant difference was observed between the midlife group and others. Conclusions  The HbA1clevel of cynomolgus monkeys was varied between different gender and age had significant differences.
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